Institution: Senckenberg Gesellschaft für Naturforschung
In a laboratory setting health and disease of plants are mainly determined on resistance factors of the plants and virulence factors of the pathogens. However, in nature the situation is more complex, as also potentially susceptible plants are usually not infected, while at times also resistant plants can show some signs of infection. It is the aim of our project to elucidate the population structure of plants and pathogens and the modifying effect of plant- and microbe-associated microbiomes for the outcome of plant-pathogen interactions.
TBG group members
- Marco Thines
- Bagdevi Mishra
- Sakshi Bharti
- Ali Tahir
- Sebastian Ploch (labmanager)
Group expertise / Methods
- Genome assemblies (including hybrid assemblies, integration of long-range information, using a variety of data and platforms (e.g. illumina, PacBio, nanopore, 10x)
- Transcriptome assemblies using various approaches
- Genome annotations
- Comparative genomics
- Functional validation of genes using genetic manipulation
- Bioinformatics (custom scipts, small programs, web-interfaces)
Thines M (2019). An evolutionary framework for host shifts–jumping ships for survival. New Phytologist, 224(2), 605-617.
Mishra B, Ploch S, Runge F, et al. (2020). The genome of Microthlaspi erraticum (Brassicaceae) provides insights into the adaptation to highly calcareous soils. Frontiers in Plant Science, 11, 943.
Thines M, Sharma R, Rodenburg SY, et al. (2020). The genome of Peronospora belbahrii reveals high heterozygosity, a low number of canonical effectors, and TC-rich promoters. Molecular Plant-Microbe Interactions, 33(5), 742-753.
Maciá-Vicente JG, Nam B, & Thines M (2020). Root filtering, rather than host identity or age, determines the composition of root-associated fungi and oomycetes in three naturally co-occurring Brassicaceae. Soil Biology and Biochemistry, 146, 107806.