LOEWE Centre for
Translational Biodiversity Genomics
Understanding the genomic basis of biodiversity
Biodiversity is the result of 3.5 billion years of evolution and one of the most complex phenomena on earth. The LOEWE Centre for Translational Biodiversity Genomics focusses on the genetic basis of biological diversity to make it accessible for basic and applied research. We sequence and study genomic variation across the tree of life to comprehend the origin and functional adaptations of diversity from genes to ecosystems (Comparative Genomics). The data addresses societal knowledge demands in applied fields, such as the genomic basis of biologically active substances (Natural Products Genomics), and the sustainable use and management of biological resources (Genomic Biomonitoring; Functional Environmental Genomics).
Genomic diversity as a basis for biodiversity
Main Objectives of TBG
- establish a new and taxonomically broad genome collection, the Senckenberg Biodiversity Genome Collection (SBGC) as an innovative digital and specimen-based museum collection
- compare genomic diversity across the tree of life to better understand the origin and functions of all levels of biological diversity (from genes to ecosystems)
- make genomic resources accessible for applied research, e.g. for a sustainable bioeconomy or natural resources management.
The joint-venture LOEWE-TBG has been initiated by the Senckenberg Nature Research Society, the Goethe University Frankfurt, the Justus Liebig University Gießen and the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and is initially funded by the LOEWE programme of the State of Hesse, Germany.
Research at the centre is divided into four project areas and numerous individual and joint projects:
The LOEWE TBG laboratory centre and a bioinformatics unit provide a powerful infrastructure for the direct implementation of projects. Their results are made available to society via technology transfer and public relations.
News
It's the mix that makes it: The complex biology of spider venom
09.09.2021
An international team of researchers around Dr. Tim Lüddecke, together with colleagues from Australia, has for the first time summarized their insights into the biology and evolution of spider venom. The article was published in the "Biological Reviews". "Spider venom is critically influenced by life stage, habitat, and especially sex. It is also the interaction of the many components rather than the action of a single toxin that makes spider venom so effective. Through their interactions, the components increase their effectiveness, literally adding up to more than the sum of their parts," says Dr. Tim Lüddecke.
For more information, see the paper or the press release at JLU. (Photo: Wolfgang Dibiasi)
Sven Winter was awarded HiFi for Accuracy SMRT Grant
23.08.2021
HiFi for Accuracy SMRT Grant program was launched by PacBio to empower scientists to make new discoveries and reach novel insights using HiFi reads.
From a pool of hundreds of submissions, PacBio selected three outstanding winners from around the world. They will use HiFi sequencing provided by local service providers to advance their fields of study. One of them is Dr. Sven Winter. The goal of his project is to generate high-quality assemblies of two giraffe species to facilitate analysis of structural differences. The HiFi for Accuracy SMRT Grant is co-sponsored by the DNA Sequencing Center at Brigham Young University, the Competence Centre for Genomic Analysis(CCGA) Kiel, and BIOTOOLS.
Congratulations, Sven!
Science meets industry - online seminar "Medicine from nature"
19.11.2021
Technologieland Hessen and LOEWE-TBG are organizing an online event called “Medikamente der Natur. Neue Wirkstoffe entdecken, entwickeln und nutzen“ (Medicines of Nature. Discovering, developing and using new active substances). The aim of the event is to give insights into the current challenges of this field by bringing together representatives from science and industry. The event will take place online, on 23. November, between 13.00 - 16.30 o'clock and will be featuring presentations from Dr. Carola Greve, Prof. Andreas Vilcinskas, Prof. Eric Helfrich and Dr. Kornelia Hardes. Input from the Pharma Industry will be provided by Prof. Paul M. Selzer, Dr. Björn Rotter and Dr. Anja Schüffler.
Please register here for the event.
More infos
What’s new at LOEWE-TBG? Find all our videos, news, press releases and selected press articles in our Newsroom. By watching our videos you can, for example, take a look into our lab center and learn more about DNA extraction or get to know TBG’s junior research groups. News include scientific results, prizes, conferences, events, job vacancies and much more. Take a look, stay tuned and follow us on Twitter @LOEWE_TBG.
You need texts or pictures about LOEWE-TBG for publication in media? Our numerous press releases and those of our partners as well as press pictures can also be found at the News Room (via Senckenberg). TBG in TV, Radio and in newspapers – we further compiled a selection of media reports.
Our partners
