The Senckenberg Nature Research Society, the Goethe-University Frankfurt, the Justus-Liebig-University Gießen and the Fraunhofer Institute for Molecular Biology and Applied Ecology IME have initiated a joint-venture to link the basic study of genomes from a broad taxonomic basis with genomics-based application.
The Centre is initially funded by Hesse’s “state initiative for the development of scientific and economic excellence” (LOEWE initiative) and was launched in January 2018.
Since 2008, the state of Hesse has been promoting outstanding future-oriented research projects with its excellence program LOEWE. Since then, 14 LOEWE centers and 54 LOEWE priorities have been selected for competitive support in competitive procedures.
ProLOEWE is the network of LOEWE research projects: they want to inform about their activities together, create short paths to their research and intensify their cooperation. An overview of the LOEWE research projects can be found at
Main objectives of LOEWE-TBG
The central focus of LOEWE-TBG is to extend biodiversity research to the genomic basis of biological diversity in order to make this diversity accessible for basic and applied research. We will achieve this objective by
- establishing a new, taxonomically broad and publicly available genome collection, the Senckenberg Biodiversity Genome Collection (SBGC) as an innovative digital and specimen-based museum collection
- comparatively studying genomics diversity across the tree of life to gain a better understanding of the origin and functions of all levels of biological diversity (from genes to ecosystems)
- making genomic resources accessible for societal-demand driven applied research, e.g. as resources for a sustainable bioeconomy or nature and species conservation.
– Strategies to optimize the analysis of gene flow in speciation at the example of giraffes, bears, whales and seals
– Disentangling a strand of silk: evolution of silk biosynthesis and associated behaviour in caddisflies
– Mobile Genetic Elements – novel treasures in unexplored genomes
– Evolution and function of species interaction networks on the example of pioneering species
Natural Products Genomics:
– Preclinical in vitro testing
– Animal Venomics
– Screening of in other subprojects identified natural products on biological activity and potential pharmaceutical application
Functional Environmental Genomics:
– Influence of anthropogenic substances on the germ cell mutation rate
– Soil Metagenomics
– MiGen Analysis: Microbiome and genome analyses of medically relevant hematophagous arthropods