Institution: Senckenberg Society for Nature Research

TBG group members

  • Marco Thines
  • Bagdevi Mishra
  • Sakshi Bharti
  • Tahir Ali
  • Sebastian Ploch (labmanager)

Landscape genomics of plant-pathogen interactions

TBG project summary

In a laboratory setting health and disease of plants are mainly determined on resistance factors of the plants and virulence factors of the pathogens. However, in nature the situation is more complex, as also potentially susceptible plants are usually not infected, while at times also resistant plants can show some signs of infection. It is the aim of our project to elucidate the population structure of plants and pathogens and the modifying effect of plant- and microbe-associated microbiomes for the outcome of plant-pathogen interactions.

Group expertise / Methods

  • Genome assemblies (including hybrid assemblies, integration of long-range information, using a variety of data and platforms (e.g. illumina, PacBio, nanopore, 10x)
  • Transcriptome assemblies using various approaches
  • Genome annotations
  • Comparative genomics
  • Phylogenomics
  • Functional validation of genes using genetic manipulation
  • Bioinformatics (custom scipts, small programs, web-interfaces)