Mobile Genetic Elements – novel treasures in unexplored genomes

Maria Nilsson

SUMMARY

In this project, the massive amounts of genome data produced at TBG will be used to explore the phylogenetic relationships of different species using mobile genetic elements. Mobile genetic elements are DNA sequences that are capable of moving around in the genome. Most genomes contain significant amounts (10-80% of total genome size) of mobile genetic elements, and these have been found to contribute to genome diversity and adaption. Many organisms lacks in depth screens of their mobile genetic element composition. We will use recently developed tools to screen genomes for known and novel mobile genetic elements. This allows understanding lineage-specific differences in mobile genetic element composition on a comparative scale, and horizontal and vertical transmissions of MGEs in extreme climates.