The research in LOEWE-TBG is organised in four project areas.

  • Comparative Genomics will improve our understanding of the origin and function of biodiversity at all levels of biological organisation.
  • Natural Product Genomics will identify potentially pharmacologically relevant substances from in silico analysis of genomic data. The candidate substances will then be tested for their biological activities by established screening pipelines.
  • Genomic monitoring will develop and extend applied genomic species detection systems for environmental monitoring and conservation. It will in particular concentrate on the quantitative detection of extracellular eDNA (environmental DNA) with genomic chip technologies.
  • Functional environmental genomics will develop new environmental monitoring systems based on changes at the molecular level, e.g. mutations, transcriptional changes or allele frequency shifts in response to anthropogenic impacts.